St. Jude Children's Research Hospital is a non-profit pediatric research institution. The mission of St. Jude is to advance cures, and means of prevention, for pediatric catastrophic diseases through research and treatment. St. Jude has launched a major initiative to advance translational science in catastrophic pediatric neurological diseases through its Pediatric Translational Neuroscience Initiative (PTNI), that aims to accelerate the development of treatments and cures and improve quality of life. Key to this effort is working closely with external stakeholders through strategic alliances across the research continuum, including industry, patient advocacy organizations, other research institutions and researchers and policy makers.