National Women’s Health Week brought an important development: the approval of a much-needed new treatment option for hot flashes caused by menopause.
The news: The U.S. Food and Drug Administration (FDA) approved Astellas Pharma’s Veozah, the first approved neurokinin 3 (NK3) receptor antagonist to treat moderate to severe hot flashes.
How it works: As estrogen levels drop during menopause, the balance between estrogen and neurokinin B (NKB), the brain chemical that regulates the body’s temperature control center, is disrupted. The drug blocks activities of the NK3 receptor, helping to better regulate body temperature, explains Bio.News.
Why it matters: Vasomotor symptoms like hot flashes and night sweats are the most common menopausal symptoms, affecting 60-80% of women in the U.S.—and some women experience significant symptoms for more than a decade after their last menstrual cycle.
A welcome development: Treatments developed specifically for menopause are sorely lacking, and hormone replacement therapy (HRT)—which is safe and effective—has long faced reputational challenges due to a flawed 2002 study that overstated risks, The New York Times recently reported.
But more research is needed—listen to this episode of the I am BIO Podcast, which explores why we need to “get uncomfortable” talking about women’s health and invest in an area of health that affects half the population.
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