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The goal of a biotechnology company is to build a revenue and profit-generating business, and here we see the spectacular and consistent revenue growth for the first generation of successful U.S. biotechnology companies - Genentech, Amgen, Biogen, Chiron and Genzyme.

Source: Annual reports for Genentech (1980-2001), Amgen (1981-2001) Biogen (1983-2001), Chiron (1985-2001), Genzyme (1985-2001)
| Underlying Data |
| Year | Revenues (in Millions) |
| 1980 | 9.000 |
| 1981 | 21.772 |
| 1982 | 36.153 |
| 1983 | 78.297 |
| 1984 | 122.839 |
| 1985 | 145.329 |
| 1986 | 202.869 |
| 1987 | 329.008 |
| 1988 | 481.591 |
| 1989 | 596.824 |
| 1990 | 994.775 |
| 1991 | 1530.697 |
| 1992 | 2234.684 |
| 1993 | 2756.897 |
| 1994 | 3257.794 |
| 1995 | 3787.271 |
| 1996 | 4466.104 |
| 1997 | 4903.309 |
| 1998 | 5733.887 |
| 1999 | 6932.835 |
| 2000 | 8020.852 |
| 2001 | 9384.900 |

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